Topological dynamics of the 2015 South Korea MERS-CoV spread-on-contact networks
Identifieur interne : 000040 ( Main/Exploration ); précédent : 000039; suivant : 000041Topological dynamics of the 2015 South Korea MERS-CoV spread-on-contact networks
Auteurs : Chang Hoon Yang ; Hyejin JungSource :
- Scientific Reports [ 2045-2322 ] ; 2020.
Abstract
Network analysis to examine infectious contact relations provides an important means to uncover the topologies of individual infectious contact networks. This study aims to investigate the spread of diseases among individuals over contact networks by exploring the 2015 Middle East Respiratory Syndrome (MERS) outbreak in Korea. We present several distinct features of MERS transmission by employing a comprehensive approach in network research to examine both the traced relationship matrix of infected individuals and their bipartite transmission routes among healthcare facilities visited for treatment. The results indicate that a few super-spreaders were more likely to hold certain structural advantages by linking to an exceptional number of other individuals, causing several ongoing transmission events in neighbourhoods without the aid of any intermediary. Thus, the infectious contact network exhibited small-world dynamics characterised by locally clustered contacts exposed to transmission paths via short path lengths. In addition, nosocomial infection analysis shows the pattern of a common-source outbreak followed by secondary person-to-person transmission of the disease. Based on the results, we suggest policy implications related to the redesign of prevention and control strategies against the spread of epidemics.
Url:
DOI: 10.1038/s41598-020-61133-9
PubMed: 32152361
PubMed Central: 7062829
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000465
- to stream Pmc, to step Curation: 000465
- to stream Pmc, to step Checkpoint: 000009
- to stream PubMed, to step Corpus: 000174
- to stream PubMed, to step Curation: 000174
- to stream PubMed, to step Checkpoint: 000040
- to stream Ncbi, to step Merge: 002597
- to stream Ncbi, to step Curation: 002597
- to stream Ncbi, to step Checkpoint: 002597
- to stream Main, to step Merge: 000043
- to stream Main, to step Curation: 000040
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Topological dynamics of the 2015 South Korea MERS-CoV spread-on-contact networks</title><author><name sortKey="Yang, Chang Hoon" sort="Yang, Chang Hoon" uniqKey="Yang C" first="Chang Hoon" last="Yang">Chang Hoon Yang</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0470 5702</institution-id><institution-id institution-id-type="GRID">grid.411199.5</institution-id><institution>Catholic Kwandong University 24,</institution></institution-wrap>Beomil-ro 579beon-gil, Gangneung-si, Gangwon-do 25601 Korea</nlm:aff><wicri:noCountry code="subfield">Gangwon-do 25601 Korea</wicri:noCountry></affiliation></author><author><name sortKey="Jung, Hyejin" sort="Jung, Hyejin" uniqKey="Jung H" first="Hyejin" last="Jung">Hyejin Jung</name><affiliation><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0719 8572</institution-id><institution-id institution-id-type="GRID">grid.262229.f</institution-id><institution>Pusan National University 2,</institution></institution-wrap>Busandaehak-ro 63beon-gil, Geumjeong-gu, Busan 46241 Korea</nlm:aff><wicri:noCountry code="subfield">Busan 46241 Korea</wicri:noCountry></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">32152361</idno><idno type="pmc">7062829</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062829</idno><idno type="RBID">PMC:7062829</idno><idno type="doi">10.1038/s41598-020-61133-9</idno><date when="2020">2020</date><idno type="wicri:Area/Pmc/Corpus">000465</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000465</idno><idno type="wicri:Area/Pmc/Curation">000465</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000465</idno><idno type="wicri:Area/Pmc/Checkpoint">000009</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000009</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:32152361</idno><idno type="wicri:Area/PubMed/Corpus">000174</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000174</idno><idno type="wicri:Area/PubMed/Curation">000174</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000174</idno><idno type="wicri:Area/PubMed/Checkpoint">000040</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000040</idno><idno type="wicri:Area/Ncbi/Merge">002597</idno><idno type="wicri:Area/Ncbi/Curation">002597</idno><idno type="wicri:Area/Ncbi/Checkpoint">002597</idno><idno type="wicri:Area/Main/Merge">000043</idno><idno type="wicri:Area/Main/Curation">000040</idno><idno type="wicri:Area/Main/Exploration">000040</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Topological dynamics of the 2015 South Korea MERS-CoV spread-on-contact networks</title><author><name sortKey="Yang, Chang Hoon" sort="Yang, Chang Hoon" uniqKey="Yang C" first="Chang Hoon" last="Yang">Chang Hoon Yang</name><affiliation><nlm:aff id="Aff1"><institution-wrap><institution-id institution-id-type="ISNI">0000 0004 0470 5702</institution-id><institution-id institution-id-type="GRID">grid.411199.5</institution-id><institution>Catholic Kwandong University 24,</institution></institution-wrap>Beomil-ro 579beon-gil, Gangneung-si, Gangwon-do 25601 Korea</nlm:aff><wicri:noCountry code="subfield">Gangwon-do 25601 Korea</wicri:noCountry></affiliation></author><author><name sortKey="Jung, Hyejin" sort="Jung, Hyejin" uniqKey="Jung H" first="Hyejin" last="Jung">Hyejin Jung</name><affiliation><nlm:aff id="Aff2"><institution-wrap><institution-id institution-id-type="ISNI">0000 0001 0719 8572</institution-id><institution-id institution-id-type="GRID">grid.262229.f</institution-id><institution>Pusan National University 2,</institution></institution-wrap>Busandaehak-ro 63beon-gil, Geumjeong-gu, Busan 46241 Korea</nlm:aff><wicri:noCountry code="subfield">Busan 46241 Korea</wicri:noCountry></affiliation></author></analytic><series><title level="j">Scientific Reports</title><idno type="eISSN">2045-2322</idno><imprint><date when="2020">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="Par1">Network analysis to examine infectious contact relations provides an important means to uncover the topologies of individual infectious contact networks. This study aims to investigate the spread of diseases among individuals over contact networks by exploring the 2015 Middle East Respiratory Syndrome (MERS) outbreak in Korea. We present several distinct features of MERS transmission by employing a comprehensive approach in network research to examine both the traced relationship matrix of infected individuals and their bipartite transmission routes among healthcare facilities visited for treatment. The results indicate that a few super-spreaders were more likely to hold certain structural advantages by linking to an exceptional number of other individuals, causing several ongoing transmission events in neighbourhoods without the aid of any intermediary. Thus, the infectious contact network exhibited small-world dynamics characterised by locally clustered contacts exposed to transmission paths via short path lengths. In addition, nosocomial infection analysis shows the pattern of a common-source outbreak followed by secondary person-to-person transmission of the disease. Based on the results, we suggest policy implications related to the redesign of prevention and control strategies against the spread of epidemics.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Bansal, S" uniqKey="Bansal S">S Bansal</name></author><author><name sortKey="Read, J" uniqKey="Read J">J Read</name></author><author><name sortKey="Pourbohloul, B" uniqKey="Pourbohloul B">B Pourbohloul</name></author><author><name sortKey="Meyers, La" uniqKey="Meyers L">LA Meyers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rolls, Da" uniqKey="Rolls D">DA Rolls</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Hertzberg, Vs" uniqKey="Hertzberg V">VS Hertzberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Watts, Dj" uniqKey="Watts D">DJ Watts</name></author><author><name sortKey="Strogatz, Sh" uniqKey="Strogatz S">SH Strogatz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Barabasi, A L" uniqKey="Barabasi A">A-L Barabási</name></author><author><name sortKey="Albert, R" uniqKey="Albert R">R Albert</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Chun, Bc" uniqKey="Chun B">BC Chun</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Li, Y" uniqKey="Li Y">Y Li</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="May, Rm" uniqKey="May R">RM May</name></author><author><name sortKey="Lloyd, Al" uniqKey="Lloyd A">AL Lloyd</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Small, M" uniqKey="Small M">M Small</name></author><author><name sortKey="Tse, Ck" uniqKey="Tse C">CK Tse</name></author><author><name sortKey="Walker, Dm" uniqKey="Walker D">DM Walker</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Newman, Mej" uniqKey="Newman M">MEJ Newman</name></author><author><name sortKey="Watts, Dj" uniqKey="Watts D">DJ Watts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Stein, Ra" uniqKey="Stein R">RA Stein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Su, S" uniqKey="Su S">S Su</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wong, G" uniqKey="Wong G">G Wong</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keeling, Mj" uniqKey="Keeling M">MJ Keeling</name></author><author><name sortKey="Eames, Ktd" uniqKey="Eames K">KTD Eames</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Mollison, D" uniqKey="Mollison D">D Mollison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Altmann, M" uniqKey="Altmann M">M Altmann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bell, Dc" uniqKey="Bell D">DC Bell</name></author><author><name sortKey="Atkinson, Js" uniqKey="Atkinson J">JS Atkinson</name></author><author><name sortKey="Carlson, Jw" uniqKey="Carlson J">JW Carlson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Keeling, Mj" uniqKey="Keeling M">MJ Keeling</name></author><author><name sortKey="Eames, Ktd" uniqKey="Eames K">KTD Eames</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ventresca, M" uniqKey="Ventresca M">M Ventresca</name></author><author><name sortKey="Aleman, D" uniqKey="Aleman D">D Aleman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pastor Satorras, R" uniqKey="Pastor Satorras R">R Pastor-Satorras</name></author><author><name sortKey="Castellano, C" uniqKey="Castellano C">C Castellano</name></author><author><name sortKey="Van Miegham, P" uniqKey="Van Miegham P">P Van Miegham</name></author><author><name sortKey="Vespignani, A" uniqKey="Vespignani A">A Vespignani</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Taylor, D" uniqKey="Taylor D">D Taylor</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Marquetoux, N" uniqKey="Marquetoux N">N Marquetoux</name></author><author><name sortKey="Stevenson, Ma" uniqKey="Stevenson M">MA Stevenson</name></author><author><name sortKey="Wilson, P" uniqKey="Wilson P">P Wilson</name></author><author><name sortKey="Ridler, A" uniqKey="Ridler A">A Ridler</name></author><author><name sortKey="Heuer, C" uniqKey="Heuer C">C Heuer</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Van Eck, Nj" uniqKey="Van Eck N">NJ van Eck</name></author><author><name sortKey="Waltman, L" uniqKey="Waltman L">L Waltman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freeman, Lc" uniqKey="Freeman L">LC Freeman</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Borgatti, Sp" uniqKey="Borgatti S">SP Borgatti</name></author><author><name sortKey="Everett, Mg" uniqKey="Everett M">MG Everett</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Seidman, S" uniqKey="Seidman S">S Seidman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hethcote, Hw" uniqKey="Hethcote H">HW Hethcote</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kim, Kh" uniqKey="Kim K">KH Kim</name></author><author><name sortKey="Tandi, Te" uniqKey="Tandi T">TE Tandi</name></author><author><name sortKey="Choi, Jw" uniqKey="Choi J">JW Choi</name></author><author><name sortKey="Moon, Jm" uniqKey="Moon J">JM Moon</name></author><author><name sortKey="Kim, Ms" uniqKey="Kim M">MS Kim</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lau, Msy" uniqKey="Lau M">MSY Lau</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cho, Sy" uniqKey="Cho S">SY Cho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lloyd Smith, Jo" uniqKey="Lloyd Smith J">JO Lloyd-Smith</name></author><author><name sortKey="Schreiber, Sj" uniqKey="Schreiber S">SJ Schreiber</name></author><author><name sortKey="Kopp, Pe" uniqKey="Kopp P">PE Kopp</name></author><author><name sortKey="Getz, Wm" uniqKey="Getz W">WM Getz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Burt, Rs" uniqKey="Burt R">RS Burt</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Rajakaruna, Sj" uniqKey="Rajakaruna S">SJ Rajakaruna</name></author><author><name sortKey="Liu, W B" uniqKey="Liu W">W-B Liu</name></author><author><name sortKey="Ding, Y B" uniqKey="Ding Y">Y-B Ding</name></author><author><name sortKey="Cao, G W" uniqKey="Cao G">G-W Cao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bernard Stoecklin, S" uniqKey="Bernard Stoecklin S">S Bernard-Stoecklin</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list></list><tree><noCountry><name sortKey="Jung, Hyejin" sort="Jung, Hyejin" uniqKey="Jung H" first="Hyejin" last="Jung">Hyejin Jung</name><name sortKey="Yang, Chang Hoon" sort="Yang, Chang Hoon" uniqKey="Yang C" first="Chang Hoon" last="Yang">Chang Hoon Yang</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/MersV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000040 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000040 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= MersV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:7062829
|texte= Topological dynamics of the 2015 South Korea MERS-CoV spread-on-contact networks
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32152361" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MersV1
| This area was generated with Dilib version V0.6.33. |  |